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SDCCAG1 Polyklonaler Antikörper

SDCCAG1 Polyklonal Antikörper für WB, IHC, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 11840-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using SDCCAG1 Polyclonal antibody (11840-1-AP)

    WB analysis using 11840-1-AP (same clone as 11840-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 11840-1-AP (SDCCAG1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11840-1-PBS in a different storage buffer formulation.

  • Immunoprecipitation (IP) experiment of A549 cells using SDCCAG1 Polyclonal antibody (11840-1-AP)

    IP experiment of A549 using 11840-1-AP (same clone as 11840-1-PBS)

    IP result of anti-SDCCAG1 (IP:11840-1-AP, 4ug; Detection:11840-1-AP 1:500) with A549 cells lysate 1800ug. This data was developed using the same antibody clone with 11840-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human lung cancer tissue using SDCCAG1 Polyclonal antibody (11840-1-AP)

    IHC staining of human lung cancer using 11840-1-AP (same clone as 11840-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 11840-1-AP (SDCCAG1 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11840-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human lung cancer tissue using SDCCAG1 Polyclonal antibody (11840-1-AP)

    IHC staining of human lung cancer using 11840-1-AP (same clone as 11840-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 11840-1-AP (SDCCAG1 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11840-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

11840-1-PBS bindet in WB, IHC, IP, Indirect ELISA SDCCAG1 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SDCCAG1 fusion protein Ag2467
Vollständiger Name serologically defined colon cancer antigen 1
Berechnetes Molekulargewicht 1076 aa, 123 kDa
Beobachtetes Molekulargewicht 130-140 kDa
GenBank-ZugangsnummerBC020794
Gene symbol SDCCAG1
Gene ID (NCBI) 9147
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SDCCAG1, also named as NEMF, is a nuclear export mediator. It can be bound to translocon-engaged 60S subunits on native ER membranes. Human SDCCAG1 has been implicated in lung cancers and it may function as a tumor suppressor gene. SDCCAG1 inactivation contributes to the transformed state of human lung cancer cells (PMID:16103875, 10575219). NEMF is also regarded as a potential biomarker for the detection of active and latent TB infections (PMID: 26818387).