SDCCAG1 Monoklonaler Antikörper

SDCCAG1 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

3C8A1

Kat-Nr. : 68708-1-PBS

Synonyme

Ribosome quality control complex subunit NEMF, NY CO 1, Nuclear export mediator factor, NEMF, Homo sapiens (Human)

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  WB analysis using 68708-1-Ig (same clone as 68708-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68708-1-Ig (SDCCAG1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68708-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

68708-1-PBS bindet in WB, Indirect ELISA SDCCAG1 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG2a
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: SDCCAG1 fusion protein Ag2467
• Vollständiger Name: serologically defined colon cancer antigen 1
• Berechnetes Molekulargewicht: 1076 aa, 123 kDa
• Beobachtetes Molekulargewicht: 130-140 kDa
• GenBank-Zugangsnummer: BC020794
• Gene symbol: SDCCAG1
• Gene ID (NCBI): 9147
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SDCCAG1, also named as NEMF, is a nuclear export mediator. It can be bound to translocon-engaged 60S subunits on native ER membranes. Human SDCCAG1 has been implicated in lung cancers and it may function as a tumor suppressor gene. SDCCAG1 inactivation contributes to the transformed state of human lung cancer cells (PMID:16103875, 10575219). NEMF is also regarded as a potential biomarker for the detection of active and latent TB infections (PMID: 26818387).