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  • KD/KO Validated

SDCCAG8 Polyklonaler Antikörper

SDCCAG8 Polyklonal Antikörper für IHC, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Hund, Maus, Ratte, Zebrafisch

Anwendung

IHC, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 13471-1-PBS

Synonyme

NPHP10, HSPC085, hCCCAP, CCCAP, BBS16

Filter:
  • Immunohistochemistry (IHC) staining of mouse brain tissue using SDCCAG8 Polyclonal antibody (13471-1-AP)

    IHC staining of mouse brain using 13471-1-AP (same clone as 13471-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 13471-1-AP (SDCCAG8 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13471-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse brain tissue using SDCCAG8 Polyclonal antibody (13471-1-AP)

    IHC staining of mouse brain using 13471-1-AP (same clone as 13471-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 13471-1-AP (SDCCAG8 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13471-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of HeLa cells using SDCCAG8 Polyclonal antibody (13471-1-AP)

    IF Staining of HeLa using 13471-1-AP (same clone as 13471-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed HeLa cells using SDCCAG8 antibody (13471-1-AP) at dilution of 1:800 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 13471-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

13471-1-PBS bindet in IHC, IF/ICC, Indirect ELISA SDCCAG8 und zeigt Reaktivität mit human, Hund, Maus, Ratten, Zebrafisch

Getestete Reaktivität human, Hund, Maus, Ratte, Zebrafisch
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SDCCAG8 fusion protein Ag4264
Vollständiger Name serologically defined colon cancer antigen 8
Berechnetes Molekulargewicht 713 aa, 83 kDa
Beobachtetes Molekulargewicht83 kDa
GenBank-ZugangsnummerBC032454
Gene symbol SDCCAG8
Gene ID (NCBI) 10806
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SDCCAG8, also named as CCCAP and NY-CO-8, plays a role in the establishment of cell polarity and epithelial lumen formation. It may play a role in ciliogenesis. Loss of SDCCAG8 function as a cause of a retinal-renal ciliopathy and validates exome capture analysis for broadly heterogeneous single-gene disorders. SDCCAG8 is localized at both centrioles and interacts directly with OFD1 (oral-facial-digital syndrome 1), which is associated with NPHP-RC. SDCCAG8 has 4 isoforms with MW 83,78,73 and 41 kDa (refer to UniProt). Catalog#13471-1-AP can recognize all the four isoforms.