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SEC14L2 Polyklonaler Antikörper

SEC14L2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32593-1-PBS

Synonyme

Alpha-tocopherol-associated protein, C22orf6, hTAP, KIAA1186, KIAA1658

Filter:
  • Western Blot (WB) analysis of various lysates using SEC14L2 Polyclonal antibody (32593-1-AP)

    WB analysis using 32593-1-AP (same clone as 32593-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 32593-1-AP (SEC14L2 antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32593-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

32593-1-PBS bindet in WB, Indirect ELISA SEC14L2 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SEC14L2 fusion protein Ag35592
Vollständiger Name SEC14-like 2 (S. cerevisiae)
Berechnetes Molekulargewicht 46 kDa
Beobachtetes Molekulargewicht44 kDa
GenBank-ZugangsnummerBC058915
Gene symbol SEC14L2
Gene ID (NCBI) 23541
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SEC14L2 (SEC14-like lipid-binding protein 2) is a cytoplasmic protein that belongs to the lipid-binding protein family. It plays an important role in a variety of cellular processes, including endosome division and lipid metabolism. SEC14L2 is able to bind phosphatidylinositol (PtdIns) and regulate its intracellular distribution, which is essential for normal endosome division. It has been shown that SEC14L2 regulates the endosome division process by promoting the conversion of PtdIns4P to PtdIns3P. In addition, SEC14L2 plays a role in the cholesterol biosynthesis pathway by stimulating squalene monooxygenase activity. In terms of viral infection, SEC14L2 is essential for hepatitis C virus (HCV) replication, and its expression promotes HCV replication in cells.