SELENBP1 Polyklonaler Antikörper

SELENBP1 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 27449-1-PBS

Synonyme

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  WB analysis using 27449-1-AP (same clone as 27449-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 27449-1-AP (SELENBP1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27449-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HEK-293 using 27449-1-AP (same clone as 27449-1-PBS)

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 27449-1-AP (SELENBP1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27449-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse liver using 27449-1-AP (same clone as 27449-1-PBS)

  mouse liver tissue were subjected to SDS PAGE followed by western blot with 27449-1-AP (SELENBP1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27449-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver cancer using 27449-1-AP (same clone as 27449-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 27449-1-AP (SELENBP1 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27449-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver cancer using 27449-1-AP (same clone as 27449-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 27449-1-AP (SELENBP1 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27449-1-PBS in a different storage buffer formulation.

• 

  IHC staining of rat liver using 27449-1-AP (same clone as 27449-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat liver tissue slide using 27449-1-AP (SELENBP1 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27449-1-PBS in a different storage buffer formulation.

• 

  IHC staining of rat liver using 27449-1-AP (same clone as 27449-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat liver tissue slide using 27449-1-AP (SELENBP1 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27449-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human colon using 27449-1-AP (same clone as 27449-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 27449-1-AP (SELENBP1 antibody) at dilution of 1:400 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27449-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

27449-1-PBS bindet in WB, IHC, Indirect ELISA SELENBP1 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: SELENBP1 fusion protein Ag24453
• Vollständiger Name: selenium binding protein 1
• Berechnetes Molekulargewicht: 52 kDa
• Beobachtetes Molekulargewicht: 56 kDa
• GenBank-Zugangsnummer: BC009084
• Gene symbol: SELENBP1
• Gene ID (NCBI): 8991
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SELENBP1 (selenium binding protein 1,SBP1), also known as LPSB or SP56, is a 472 amino acid peripheral membrane protein that binds selenium covalently. Selenium, an essential trace element, has been shown to have an anti-cancer effect. Many reports have described a relationship between insufficient selenium intake and increased risk of cancer. Moreover, the expression of SELENBP1 has been shown to be decreased in several tumors including cancers of the prostate, lungs, colon, and ovary (PMID: 21143902, 20332323, 18272210). SELENBP1 has four isoforms with the molecular mass of 56kD, 52kD and 45kD.