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SEMA6B Polyklonaler Antikörper

SEMA6B Polyklonal Antikörper für WB, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 22571-1-PBS

Synonyme

SEM SEMA Y, SEMA VIB, Sema Z, SEMAN, Semaphorin 6B

Filter:
  • Western Blot (WB) analysis of various lysates using SEMA6B Polyclonal antibody (22571-1-AP)

    WB analysis using 22571-1-AP (same clone as 22571-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 22571-1-AP (SEMA6B antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22571-1-PBS in a different storage buffer formulation.

  • Immunoprecipitation (IP) experiment of mouse brain tissue using SEMA6B Polyclonal antibody (22571-1-AP)

    IP experiment of mouse brain using 22571-1-AP (same clone as 22571-1-PBS)

    IP result of anti-SEMA6B (IP:22571-1-AP, 4ug; Detection:22571-1-AP 1:1000) with mouse brain tissue lysate 1120 ug. This data was developed using the same antibody clone with 22571-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

22571-1-PBS bindet in WB, IP, Indirect ELISA SEMA6B und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SEMA6B fusion protein Ag16707
Vollständiger Name sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
Berechnetes Molekulargewicht95, 74 kDa
Beobachtetes Molekulargewicht70 kDa
GenBank-ZugangsnummerBC142617
Gene symbol SEMA6B
Gene ID (NCBI) 10501
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-affinitätsgereinigt
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Semaphorins (SEMAs) play critical roles in inflammation, angiogenesis, apoptosis, fibrosis, bone remodeling, and cell invasion. SEMA6B, the sixth member of the SEMA family, has shown significant correlations with the stage of liver fibrosis in hepatitis C virus-infected patients. SEMA6B is also involved in inflammatory responses and serves as a biomarker for macrophage-specific genes. Additionally, the level of SEMA6B in circulating monocytes has predictive value for cardiovascular disease. Also, SEMA6B can be a valuable biomarker for diagnosing HBV-ACLF12 (PMID: 39267780).