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SENP2 Polyklonaler Antikörper

SENP2 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 29772-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using SENP2 Polyclonal antibody (29772-1-AP)

    WB analysis using 29772-1-AP (same clone as 29772-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 29772-1-AP (SENP2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29772-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human pancreas cancer tissue using SENP2 Polyclonal antibody (29772-1-AP)

    IHC staining of human pancreas cancer using 29772-1-AP (same clone as 29772-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 29772-1-AP (SENP2 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29772-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

29772-1-PBS bindet in WB, IHC, Indirect ELISA SENP2 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SENP2 fusion protein Ag30728
Vollständiger Name SUMO1/sentrin/SMT3 specific peptidase 2
Berechnetes Molekulargewicht 68 kDa
Beobachtetes Molekulargewicht60-68 kDa
GenBank-ZugangsnummerNM_021627
Gene symbol SENP2
Gene ID (NCBI) 59343
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SENP2 (Sentrin-specific protease 2), as a protease, catalyzes two essential functions in the SUMO pathway. The first is the hydrolysis of an alpha-linked peptide bond at the C-terminal end of the small ubiquitin-like modifier (SUMO) propeptides, SUMO1, SUMO2 and SUMO3 leading to the mature form of the proteins (PMID:15296745). The second is the deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins, by cleaving an epsilon-linked peptide bond between the C-terminal glycine of the mature SUMO and the lysine epsilon-amino group of the target protein (PMID:20194620, PMID:21965678). It has 2 isoforms with the molecular weight of 66 and 68 kDa.