Serpin E1/PAI-1 Rekombinanter Antikörper

Serpin E1/PAI-1 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

243115E1

Kat-Nr. : 85683-6-PBS

Synonyme

PAI-1, SERPINE1, SERPINE1, PAI-1, PAI, PAI 1

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  WB analysis using 85683-6-RR (same clone as 85683-6-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85683-6-RR (SERPINE1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85683-6-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

85683-6-PBS bindet in WB, Indirect ELISA Serpin E1/PAI-1 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Serpin E1/PAI-1 fusion protein Eg3798
• Vollständiger Name: serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
• Berechnetes Molekulargewicht: 402 aa, 45 kDa
• Beobachtetes Molekulargewicht: 45 kDa
• GenBank-Zugangsnummer: BC010860
• Gene symbol: PAI-1
• Gene ID (NCBI): 5054
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SERPINE1, also named as Plasminogen activator inhibitor type 1 (PAI-1), is a member of the serine protease inhibitor (SERPIN) superfamily. PAI-1 is the principal inhibitor of tPA and uPA, and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia.