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SERPING1/C1 Inactivator Rekombinanter Antikörper

SERPING1/C1 Inactivator Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

3H7

Kat-Nr. : 82731-1-PBS

Synonyme

Serpin G1, SERPING1, C1-inhibiting factor, C1IN, C1 inhibiting factor

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  • Western Blot (WB) analysis of human plasma using SERPING1/C1 Inactivator Recombinant antibody (82731-1-RR)

    WB analysis of human plasma using 82731-1-RR (same clone as 82731-1-PBS)

    human plasma were subjected to SDS PAGE followed by western blot with 82731-1-RR (SERPING1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82731-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

82731-1-PBS bindet in WB, Indirect ELISA SERPING1/C1 Inactivator und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen SERPING1/C1 Inactivator fusion protein Ag2819
Vollständiger Name serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
Berechnetes Molekulargewicht 500 aa, 55 kDa
Beobachtetes Molekulargewicht 100 kDa
GenBank-ZugangsnummerBC011171
Gene symbol SERPING1
Gene ID (NCBI) 710
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SERPING1, also known as C1 Inhibitor (C1INH), is a member of the Serine proteinase inhibitor family. Its main function is the inhibition of the complement system to prevent spontaneous activation. It inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). C1INH is the most heavily glycosylated plasma protein. Of its 95-105 kDa apparent molecular mass, the protein moiety of 500 aa accounts for only 55 kDa. The native 105 kDa form of C1INH could be cleaved into 60-65 kDa fragments.