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SESN1 Rekombinanter Antikörper

SESN1 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250470G1

Kat-Nr. : 86008-1-PBS

Synonyme

EC:1.11.1.-, p53 regulated protein PA26, p53-regulated protein PA26, PA26, SEST1

Filter:
  • Western Blot (WB) analysis of various lysates using SESN1 Recombinant antibody (86008-1-RR)

    WB analysis using 86008-1-RR (same clone as 86008-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86008-1-RR (SESN1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86008-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 86008-1-RR

    Affinity and Kinetic Characterization of 86008-1-RR

    Biolayer interferometry (BLl) kinetic assays of 86008-1-RR against Human SESN1 were performed. The affinity constant is 1.01 nM.

Geprüfte Anwendungen

Produktinformation

86008-1-PBS bindet in WB, Indirect ELISA SESN1 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen SESN1 fusion protein Ag16462
Vollständiger Name sestrin 1
Berechnetes Molekulargewicht 551 aa, 64 kDa
Beobachtetes Molekulargewicht66 kDa
GenBank-ZugangsnummerBC112036
Gene symbol SESN1
Gene ID (NCBI) 27244
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Sestrins, including sestrin-1 (PA26), sestrin-2 (Hi95), and sestrin-3, are 48 to 65 kDa cystein sulfinyl reductases and they modulate peroxide signaling and antioxidant defense. These proteins selectively reduce or repair hyperoxidized forms of typical 2-Cys peroxiredoxins within eukaryotes. Expression of these proteins is regulated by p53, a tumor suppressor protein. Sestrin 1 is implicated in the inhibition of cell growth. It is approximately a 66kDa protein in humans (551 amino acids).