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SFRP5 Polyklonaler Antikörper

SFRP5 Polyklonal Antikörper für IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 19177-1-PBS

Synonyme

Frizzled related protein 1b, Frizzled-related protein 1b, FRP1B, FRP-1b, SARP3

Filter:
  • Immunohistochemistry (IHC) staining of human thyroid cancer tissue using SFRP5 Polyclonal antibody (19177-1-AP)

    IHC staining of human thyroid cancer using 19177-1-AP (same clone as 19177-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 19177-1-AP (SFRP5 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19177-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human cervical cancer tissue using SFRP5 Polyclonal antibody (19177-1-AP)

    IHC staining of human cervical cancer using 19177-1-AP (same clone as 19177-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 19177-1-AP (SFRP5 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19177-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human cervical cancer tissue using SFRP5 Polyclonal antibody (19177-1-AP)

    IHC staining of human cervical cancer using 19177-1-AP (same clone as 19177-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 19177-1-AP (SFRP5 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19177-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

19177-1-PBS bindet in IHC, Indirect ELISA SFRP5 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SFRP5 fusion protein Ag5715
Vollständiger Name secreted frizzled-related protein 5
Berechnetes Molekulargewicht 36 kDa
GenBank-ZugangsnummerBC050435
Gene symbol SFRP5
Gene ID (NCBI) 6425
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Secreted frizzled-related protein 5 (SFRP5) is an anti-inflammatory adipokine whose expression is perturbed in models of obesity and type 2 diabetes. SFRP5 is secreted by adipocytes and that it controls the micro-environment of white adipose tissue under conditions of metabolic stress (PMID: 20558665). SFRP5 gene consists of 317 amino acid residues and 3 coding exons and maps to chromosome 10q24.1 in humans. SFRP5 was initially found to be highly expressed in retinal pigment epithelium cells and moderately expressed in the pancreas. SFRP5 is involved in the pathological process of obesity, insulin resistance, dyslipidemia, inflammation, and fibrosis and is associated with obesity, T2D, and ASCVD (PMID: 31199714, PMID: 32004418).