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SFRS2 Polyklonaler Antikörper

SFRS2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 21212-1-PBS

Synonyme

Serine/arginine-rich splicing factor 2, SC-35, SC35, SC 35, Protein PR264

Filter:
  • Western Blot (WB) analysis of various lysates using SFRS2 Polyclonal antibody (21212-1-AP)

    WB analysis using 21212-1-AP (same clone as 21212-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 21212-1-AP (SFRS2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21212-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

21212-1-PBS bindet in WB, Indirect ELISA SFRS2 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SFRS2 fusion protein Ag15612
Vollständiger Name splicing factor, arginine/serine-rich 2
Berechnetes Molekulargewicht 221 aa, 25 kDa
Beobachtetes Molekulargewicht30-35 kDa
GenBank-ZugangsnummerBC070086
Gene symbol SFRS2
Gene ID (NCBI) 6427
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SFRS2, also named as PR264 and SC-35, belongs to the splicing factor SR family. SFRS2 is necessary for the splicing of pre-mRNA. It is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. It binds to purine-rich RNA sequences, either 5'-AGSAGAGTA-3' (S=C or G) or 5'-GTTCGAGTA-3'. SFRS2 can bind to beta-globin mRNA and commit it to the splicing pathway. The antibody has no cross reaction to SFRS2B.