SRp20 Polyklonaler Antikörper

SRp20 Polyklonal Antikörper für IHC, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus und mehr (1)

Anwendung

WB, IHC, ELISA

Konjugation

Unkonjugiert

Publikationen(5)

Kat-Nr. : 10916-1-AP

Synonyme

SFRS3, Pre-mRNA-splicing factor SRP20, Serine/arginine-rich splicing factor 3, SFRS 3, Splicing factor, arginine/serine-rich 3

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  IHC staining of human cervical cancer using 10916-1-AP

  Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 10916-1-AP (SRp20 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IHC staining of human cervical cancer using 10916-1-AP

  Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 10916-1-AP (SRp20 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IHC staining of mouse testis using 10916-1-AP

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 10916-1-AP (SRp20 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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Geprüfte Anwendungen

• Erfolgreiche Detektion in IHC: humanes Zervixkarzinomgewebe, Maushodengewebe; Hinweis: Antigendemaskierung mit TE-Puffer pH 9,0 empfohlen. (*) Wahlweise kann die Antigendemaskierung auch mit Citratpuffer pH 6,0 erfolgen.

Empfohlene Verdünnung

• Immunhistochemie (IHC): IHC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• WB: See 3 publications below
• IHC: See 2 publications below

Produktinformation

10916-1-AP bindet in WB, IHC, ELISA SRp20 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• In Publikationen genannte Reaktivität: human, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: SRp20 fusion protein Ag1341
• Vollständiger Name: splicing factor, arginine/serine-rich 3
• Berechnetes Molekulargewicht: 20 kDa
• GenBank-Zugangsnummer: BC000914
• Gene symbol: SRSF3
• Gene ID (NCBI): 6428
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SFRS3, also named as SRSF3 and SRP20, belongs to the splicing factor SR family. It may be involved in RNA processing in relation with cellular proliferation and/or maturation. SFRS3 is one of the cognate factors. It is a proto-oncogene critical for cell proliferation and tumor induction and maintenance.The MW of SFRS3 is 20kd.

Publikationen

Species	Application	Title
human	WB,IHC	Gastroenterology; Proteomic characterization identifies clinically relevant subgroups of gastrointestinal stromal tumors; Authors - Mingjun Sun
		Mol Cell; Cross-Regulation between TDP-43 and Paraspeckles Promotes Pluripotency-Differentiation Transition.; Authors - Miha Modic
human	IHC	Front Oncol; SRSF3 Expression Serves as a Potential Biomarker for Prognostic and Immune Response in Pan-Cancer.; Authors - Zihua Li
human	WB	Pathol Res Pract; LINC01210 promotes malignant phenotypes of colorectal cancer through epigenetically upregulating SRSF3.; Authors - Jia Luo
rat	WB	Rev Port Cardiol; Mesenchymal stem cells may alleviate angiotensin II-induced myocardial fibrosis and hypertrophy by upregulating SFRS3 expression; Authors - Ling Gu