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SFRS6 Polyklonaler Antikörper

SFRS6 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 11772-1-PBS

Synonyme

Pre-mRNA-splicing factor SRP55, Serine/arginine-rich splicing factor 6, Splicing factor, arginine/serine-rich 6, SRP55, SRSF6

Filter:
  • Western Blot (WB) analysis of various lysates using SFRS6 Polyclonal antibody (11772-1-AP)

    WB analysis using 11772-1-AP (same clone as 11772-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 11772-1-AP (SFRS6 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11772-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

11772-1-PBS bindet in WB, Indirect ELISA SFRS6 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SFRS6 fusion protein Ag2412
Vollständiger Name splicing factor, arginine/serine-rich 6
Berechnetes Molekulargewicht 344 aa, 40 kDa
Beobachtetes Molekulargewicht40 kDa
GenBank-ZugangsnummerBC006832
Gene symbol SFRS6
Gene ID (NCBI) 6431
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SR proteins have a characteristic C-terminal Ser/Arg-rich repeat (RS domain) of variable length and constitute a family of highly conserved nuclear phosphoproteins that can function as both essential and alternative pre-mRNA splicing factors [PMID:7556075]. SRFS6 has a pivotal role in the TF exon 5 definition, an event essential for flTF biosynthesis. Besides, up- or down regulation of SRSF6 alters the splicing of several tumor suppressors and oncogenes to generate the oncogenic isoforms and reduce the tumor suppressive isoforms [PMID:23132731].