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SGLT3/SLC5A4 Polyklonaler Antikörper

SGLT3/SLC5A4 Polyklonal Antikörper für WB, IHC, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 24327-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of mouse kidney tissue using SGLT3/SLC5A4 Polyclonal antibody (24327-1-AP)

    WB analysis of mouse kidney using 24327-1-AP (same clone as 24327-1-PBS)

    mouse kidney tissue were subjected to SDS PAGE followed by western blot with 24327-1-AP (SGLT3/SLC5A4 antibody at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24327-1-PBS in a different storage buffer formulation.

  • Immunoprecipitation (IP) experiment of mouse kidney tissue using SGLT3/SLC5A4 Polyclonal antibody (24327-1-AP)

    IP experiment of mouse kidney using 24327-1-AP (same clone as 24327-1-PBS)

    IP result of anti-SGLT3/SLC5A4 (IP:24327-1-AP, 4ug; Detection:24327-1-AP 1:500) with mouse kidney tissue lysate 4000ug. This data was developed using the same antibody clone with 24327-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human kidney tissue using SGLT3/SLC5A4 Polyclonal antibody (24327-1-AP)

    IHC staining of human kidney using 24327-1-AP (same clone as 24327-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney slide using 24327-1-AP (SGLT3/SLC5A4 antibody at dilution of 1:50. This data was developed using the same antibody clone with 24327-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human kidney tissue using SGLT3/SLC5A4 Polyclonal antibody (24327-1-AP)

    IHC staining of human kidney using 24327-1-AP (same clone as 24327-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney slide using 24327-1-AP (SGLT3/SLC5A4 antibody at dilution of 1:50. This data was developed using the same antibody clone with 24327-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

24327-1-PBS bindet in WB, IHC, IP, Indirect ELISA SGLT3/SLC5A4 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SGLT3/SLC5A4 fusion protein Ag19391
Vollständiger Name solute carrier family 5 (low affinity glucose cotransporter), member 4
Berechnetes Molekulargewicht 659 aa, 72 kDa
Beobachtetes Molekulargewicht 60-70 kDa
GenBank-ZugangsnummerBC153069
Gene symbol SGLT3
Gene ID (NCBI) 6527
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SLC5A4, also known as SGLT3, is a sugar sensor that depolarizes the plasma membrane in response to external glucose (PMID: 12748858, 20421923). SGLT3 mediates the influx of sodium ions into the cell but does not transport sugars, also potently activated by imino sugars such as deoxynojirimycin (PMID: 22766068, 13130073). SGLT3 is a plasma membrane protein, shares 70% identity with SGLT1, and is expressed in the small intestine (cholinergic neurons), skeletal muscle, kidney, uterus, and testis (PMID: 12748858). SGLT3 protein at apparent molecular masses of 72 kDa and 80 kDa in human kidney tissue and HK-2 cells (PMID: 22766068).