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SH2D1A Polyklonaler Antikörper

SH2D1A Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 11868-1-PBS

Synonyme

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  • Western Blot (WB) analysis of mouse thymus tissue using SH2D1A Polyclonal antibody (11868-1-AP)

    WB analysis of mouse thymus using 11868-1-AP (same clone as 11868-1-PBS)

    mouse thymus tissue were subjected to SDS PAGE followed by western blot with 11868-1-AP (SH2D1A antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11868-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of Jurkat cells using SH2D1A Polyclonal antibody (11868-1-AP)

    WB analysis of Jurkat using 11868-1-AP (same clone as 11868-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 11868-1-AP (SH2D1A Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11868-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

11868-1-PBS bindet in WB, Indirect ELISA SH2D1A und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SH2D1A fusion protein Ag2450
Vollständiger Name SH2 domain protein 1A
Berechnetes Molekulargewicht 128 aa, 14 kDa
Beobachtetes Molekulargewicht 16 kDa
GenBank-ZugangsnummerBC020732
Gene symbol SH2D1A
Gene ID (NCBI) 4068
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SH2D1A, also named as DSHP and SAP, is an inhibitor of the SLAM self-association. It acts by blocking recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to a docking site in the SLAM cytoplasmic region. SH2D1A mediates interaction between FYN and SLAMF1. Defects in SH2D1A are a cause of lymphoproliferative syndrome X-linked type 1 (XLP1).