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SHANK3 Polyklonaler Antikörper

SHANK3 Polyklonal Antikörper für ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 55058-1-AP

Synonyme

DEL22q13.3, KIAA1650, PROSAP2, PSAP2, sczd15, SHANK3, SPANK 2

Geprüfte Anwendungen

Produktinformation

55058-1-AP bindet in ELISA SHANK3 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Peptid
Vollständiger Name SH3 and multiple ankyrin repeat domains 3
Berechnetes Molekulargewicht 186 kDa
GenBank-ZugangsnummerNM_001080420
Gene symbol SHANK3
Gene ID (NCBI) 85358
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS with 0.02% sodium azide and 50% glycerol
LagerungsbedingungenBei -20℃ lagern. Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SHANK3, also named as KIAA1650 and PSAP2, seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. SHANK3 may play a role in the structural and functional organization of the dendritic spine and synaptic junction. The antibody is specific to SHANK3.