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SHARPIN Monoklonaler Antikörper

SHARPIN Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

3A9E2

Kat-Nr. : 67177-1-PBS

Synonyme

DKFZp434N1923, hSIPL1, SHARPIN, SIPL1

Filter:
  • Western Blot (WB) analysis of various lysates using SHARPIN Monoclonal antibody (67177-1-Ig)

    WB analysis using 67177-1-Ig (same clone as 67177-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67177-1-Ig (SHARPIN antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67177-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using SHARPIN Monoclonal antibody (67177-1-Ig)

    WB analysis using 67177-1-Ig (same clone as 67177-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67177-1-Ig (SHARPIN antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67177-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

67177-1-PBS bindet in WB, Indirect ELISA SHARPIN und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG2a
Klonalität Monoklonal
Typ Antikörper
Immunogen SHARPIN fusion protein Ag6367
Vollständiger Name SHANK-associated RH domain interactor
Berechnetes Molekulargewicht 40 kDa
Beobachtetes Molekulargewicht 40 kDa
GenBank-ZugangsnummerBC025244
Gene symbol SHARPIN
Gene ID (NCBI) 81858
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SHARPIN is as a third component of the linear ubiquitin chain assembly complex (LUBAC), recruited to the CD40 and TNF receptor signaling complexes together with its other constituents, HOIL1 and HOIP(PMID:21455173).SHARPIN is enriched in the postsynaptic density and forms a complex with SHANK in heterologous cells and brain(PMID:11178875).It has 2 isoforms produced by alternative splicing.