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SHB Polyklonaler Antikörper

SHB Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31967-1-PBS

Synonyme

SH2 domain-containing adapter protein B

Filter:
  • Western Blot (WB) analysis of various lysates using SHB Polyclonal antibody (31967-1-AP)

    WB analysis using 31967-1-AP (same clone as 31967-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 31967-1-AP (SHB antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31967-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

31967-1-PBS bindet in WB, Indirect ELISA SHB und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SHB fusion protein Ag35936
Vollständiger Name Src homology 2 domain containing adaptor protein B
Berechnetes Molekulargewicht55 kDa
Beobachtetes Molekulargewicht55 kDa
GenBank-ZugangsnummerBC136581
Gene symbol SHB
Gene ID (NCBI) 6461
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SH2 domain-containing adapter protein B (SHB) is an adaptor protein that operates downstream of tyrosine kinases. It is crucial in various cellular responses, including cell survival, differentiation, and proliferation (PMID: 29792386). SHB is involved in the modulation of focal adhesion kinase (FAK) signaling, which is important for regulating cell cycle progression in hematopoietic stem cells (PMID: 23528453). The protein has also been implicated in the progression of myeloproliferative disorders by affecting the activity of FAK and other signaling intermediates (PMID: 24952416).