SHBG Polyklonaler Antikörper

SHBG Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 18200-1-PBS

Synonyme

Testosterone-estradiol-binding globulin, Testis-specific androgen-binding protein, Sex steroid-binding protein, Sex steroid binding protein, Sex hormone-binding globulin

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  WB analysis using 18200-1-AP (same clone as 18200-1-PBS)

  human plasma were subjected to SDS PAGE followed by western blot with 18200-1-AP (SHBG antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18200-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver using 18200-1-AP (same clone as 18200-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 18200-1-AP (SHBG antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18200-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse testis using 18200-1-AP (same clone as 18200-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 18200-1-AP (SHBG antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18200-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

18200-1-PBS bindet in WB, IHC, Indirect ELISA SHBG und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: SHBG fusion protein Ag12683
• Vollständiger Name: sex hormone-binding globulin
• Berechnetes Molekulargewicht: 402 aa, 44 kDa
• Beobachtetes Molekulargewicht: 42-44 kDa
• GenBank-Zugangsnummer: BC101785
• Gene symbol: SHBG
• Gene ID (NCBI): 6462
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SHBG (sex hormone-binding globulin), also known as androgen-binding protein (ABP), is the specific transport protein for sex steroid hormones in humans. SHBG is synthesized mainly by the liver and circulates in the blood, in form of homodimer with a single steroid-binding site per dimer. In addition to the plasma SHBG, a testis isoform expressed by Sortoli cells also exists due to the gene alternative splicing. Various bands (44-56 kDa) recognized by this antibody may represent variably glycosylated or different isoforms of SHBG.