DSS1 Polyklonaler Antikörper

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• KD/KO Validated

DSS1 Polyklonal Antikörper für IHC, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IF, IHC, ELISA

Konjugation

Unkonjugiert

Publikationen(9)

Kat-Nr. : 13639-1-AP

Synonyme

DSS1, ECD, SEM1, SHFD1, Shfdg1, SHFM1, SHSF1

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  IHC staining of human skin cancer using 13639-1-AP

  Immunohistochemical analysis of paraffin-embedded human skin cancer tissue slide using 13639-1-AP (DSS1 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IHC staining of human skin cancer using 13639-1-AP

  Immunohistochemical analysis of paraffin-embedded human skin cancer tissue slide using 13639-1-AP (DSS1 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

• 

  IHC staining of human cervical cancer using 13639-1-AP

  Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 13639-1-AP (DSS1 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

• 

  IHC staining of human placenta using 13639-1-AP

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 13639-1-AP (DSS1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

• 

  IHC staining of human placenta using 13639-1-AP

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 13639-1-AP (DSS1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

• 

  IHC staining of human cervical cancer using 13639-1-AP

  Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 13639-1-AP (DSS1 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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Geprüfte Anwendungen

• Erfolgreiche Detektion in IHC: humanes Hautkrebsgewebe, humanes Zervixkarzinomgewebe, humanes Plazenta-Gewebe; Hinweis: Antigendemaskierung mit TE-Puffer pH 9,0 empfohlen. (*) Wahlweise kann die Antigendemaskierung auch mit Citratpuffer pH 6,0 erfolgen.

Empfohlene Verdünnung

• Immunhistochemie (IHC): IHC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• KD/KO: See 2 publications below
• WB: See 7 publications below
• IHC: See 3 publications below
• IF: See 1 publications below

Produktinformation

13639-1-AP bindet in WB, IF, IHC, ELISA DSS1 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• In Publikationen genannte Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: DSS1 fusion protein Ag4573
• Vollständiger Name: split hand/foot malformation (ectrodactyly) type 1
• Berechnetes Molekulargewicht: 70 aa, 8 kDa
• GenBank-Zugangsnummer: BC032782
• Gene symbol: DSS1
• Gene ID (NCBI): 7979
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Publikationen

Species	Application	Title
human	WB	Nature; BRCA2 prevents R-loop accumulation and associates with TREX-2 mRNA export factor PCID2.; Authors - Vaibhav Bhatia ; KD Validated
human	WB, IF	EMBO J; The proteasomal de-ubiquitinating enzyme POH1 promotes the double-strand DNA break response.; Authors - Laura R Butler
		J Med Genet; Absent expression of the osteoblast-specific maternally imprinted genes, DLX5 and DLX6, causes split hand/split foot malformation type I.; Authors - Sawitree Rattanasopha
human	IHC	Lab Invest; Increased chemosensitivity via BRCA2-independent DNA damage in DSS1- and PCID2-depleted breast carcinomas.; Authors - Naomi Gondo ; KD Validated
human	WB	BMC Cancer; Breast cancers with high DSS1 expression that potentially maintains BRCA2 stability have poor prognosis in the relapse-free survival.; Authors - Andri Rezano
human	WB	Protein Cell; DSSylation, a novel protein modification targets proteins induced by oxidative stress, and facilitates their degradation in cells.; Authors - Yinghao Zhang