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SKOR2 Polyklonaler Antikörper

SKOR2 Polyklonal Antikörper für WB, IHC, IF-P, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, IF-P, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 55370-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using SKOR2 Polyclonal antibody (55370-1-AP)

    WB analysis using 55370-1-AP (same clone as 55370-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 55370-1-AP (SKOR2 antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55370-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse cerebellum tissue using SKOR2 Polyclonal antibody (55370-1-AP)

    IHC staining of mouse cerebellum using 55370-1-AP (same clone as 55370-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 55370-1-AP (SKOR2 antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 55370-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse cerebellum tissue using SKOR2 Polyclonal antibody (55370-1-AP)

    IHC staining of mouse cerebellum using 55370-1-AP (same clone as 55370-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 55370-1-AP (SKOR2 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 55370-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of mouse cerebellum tissue using SKOR2 Polyclonal antibody (55370-1-AP)

    IF Staining of mouse cerebellum using 55370-1-AP (same clone as 55370-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse cerebellum tissue using SKOR2 antibody (55370-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 55370-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

55370-1-PBS bindet in WB, IHC, IF-P, Indirect ELISA SKOR2 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Peptid
Vollständiger Name functional smad suppressing element 18
Berechnetes Molekulargewicht 104 kDa
Beobachtetes Molekulargewicht30kDa, 60 kDa
GenBank-ZugangsnummerXM_001715219
Gene symbol SKOR2
Gene ID (NCBI) 652991
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SKOR2 (SKI family transcriptional corepressor 2), also named FUSSEL18, is a transcriptional repressor that is highly expressed in the central nervous system (PMID: 16200078). SKOR2 was detected at 30 and 60 kD in the cerebellum. It is identified as a novel transcriptional regulator in Purkinje cells that acts upstream of Shh during cerebellum development (PMID: 21937600). Skor2 was detected in Purkinje cells in the human fetal cerebellum (PMID: 34140698).