SLA2 Polyklonaler Antikörper

SLA2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 14152-1-PBS

Synonyme

Src like adapter 2, SLAP-2, SLAP2, SLAP 2, MARS

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  WB analysis using 14152-1-AP (same clone as 14152-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 14152-1-AP (SLA2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14152-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

14152-1-PBS bindet in WB, Indirect ELISA SLA2 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: SLA2 fusion protein Ag5334
• Vollständiger Name: Src-like-adaptor 2
• Berechnetes Molekulargewicht: 261 aa, 29 kDa
• Beobachtetes Molekulargewicht: 28-30 kDa
• GenBank-Zugangsnummer: BC042041
• Gene symbol: SLA2
• Gene ID (NCBI): 84174
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SLA2 is an adapter protein, which negatively regulates T-cell receptor (TCR) signaling. It Inhibits T-cell antigen-receptor-induced activation of nuclear factor of activated T-cells and may act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL-dependent degradation of signaling proteins (PMID: 11696592).