SLAMF6 Rekombinanter Antikörper

SLAMF6 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

251099G11

Kat-Nr. : 98541-1-RR

Synonyme

CD352, Ly108, Lymphocyte antigen 108, SLAM family member 6

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  FC experiment of mouse splenocytes using 98541-1-RR

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse SLAMF6 Rabbit RecAb (98541-1-RR, Clone: 251099G11) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with 0.25 ug APC Anti-Mouse CD45R (B220) (RA3-6B2) (APC-65139, Clone: RA3-6B2). Cells were not fixed.

• 

  FC experiment of mouse splenocytes using 98541-1-RR

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse SLAMF6 Rabbit RecAb (98541-1-RR, Clone:251099G11) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: Maus-Splenozyten

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

98541-1-RR bindet in FC SLAMF6 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: SLAMF6 fusion protein Eg5249
• Vollständiger Name: SLAM family member 6
• Berechnetes Molekulargewicht: 36 kDa
• GenBank-Zugangsnummer: NM_030710.2
• Gene symbol: Slamf6
• Gene ID (NCBI): 30925
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2 - 8°C. Stable for one year after shipment.

Hintergrundinformationen

Signaling lymphocyte activation molecule 6 (SLAMF6) (Ly108 in mice, NTB-A or SF2000 in humans) is a homophilic receptor belonging to the superfamily immunoglobulin (Ig) domain-containing molecules (PMID:31199820). SLAMF6 is a type I transmembrane protein with two extracellular immunoglobins (Ig)-like domains and three cytoplasmic tyrosine-based signaling motifs, one of which is immunoreceptor tyrosine-based switch motif (PMID:31315913). SLAMF6 is expressed on a wide variety of immune cells including T cells (also TFH), B cells, NK cells (expressed in humans only), double positive thymocytes, eosinophils, and neutrophils (mouse only) (PMID:11862385).