SLC14A2 Polyklonaler Antikörper

SLC14A2 Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 21932-1-AP

Synonyme

hUT A6, HUT2, SLC14A2, Urea transporter 2, Urea transporter, kidney, UT A2, UT2, UTA, UTR

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Galerie der Validierungsdaten

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  WB analysis using 21932-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 21932-1-AP (SLC14A2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

• 

  WB analysis using 21932-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 21932-1-AP (SLC14A2 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: Maushirngewebe, humanes Hirngewebe

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:1000-1:4000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

21932-1-AP bindet in WB, ELISA SLC14A2 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: SLC14A2 fusion protein Ag16561
• Vollständiger Name: solute carrier family 14 (urea transporter), member 2
• Berechnetes Molekulargewicht: 920 aa, 101 kDa
• Beobachtetes Molekulargewicht: 43 kDa, 101 kDa
• GenBank-Zugangsnummer: BC110445
• Gene symbol: SLC14A2
• Gene ID (NCBI): 8170
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SLC14A2, also known as human urea transporter -2 (HUT2), is the human homolog of UT-A2 and the only kidney-specific urea transporter cloned in humans. Urea transport in the kidney is mediated by a family of transporter proteins, including renal urea transporters (UT-A) and erythrocyte urea transporters (UT-B). UT-A proteins expressed in the kidney play a critical role in generating the hypertonic medulla, which is an integral component of the urinary concentrating mechanism (PMID: 11590132, 11880324). The 4.2-kb hUT-A1 cDNA encodes a 920-amino acid peptide, which is 89% identical to the rat UT-A1 protein (PMID: 11502588).