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MCT2/SLC16A7 Rekombinanter Antikörper

MCT2/SLC16A7 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242811F6

Kat-Nr. : 85145-3-PBS

Synonyme

SLC16A7, MCT 2, MCT2, Monocarboxylate transporter 2, Solute carrier family 16 member 7

Filter:
  • Western Blot (WB) analysis of various lysates using MCT2/SLC16A7 Recombinant antibody (85145-3-RR)

    WB analysis using 85145-3-RR (same clone as 85145-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85145-3-RR (SLC16A7 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85145-3-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 85145-3-RR

    Affinity and Kinetic Characterization of 85145-3-RR

    Biolayer interferometry (BLl) kinetic assays of 85145-3-RR against Human MCT2/SLC16A7 were performed. The affinity constant is 37.0 nM.

Geprüfte Anwendungen

Produktinformation

85145-3-PBS bindet in WB, Indirect ELISA MCT2/SLC16A7 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen MCT2/SLC16A7 fusion protein Ag14201
Vollständiger Name solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
Berechnetes Molekulargewicht 478 aa, 52 kDa
Beobachtetes Molekulargewicht40-52 kDa
GenBank-ZugangsnummerBC030693
Gene symbol MCT2
Gene ID (NCBI) 9194
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SLC16A7, also named MCT2, is a proton-coupled monocarboxylate transporter catalyzing the rapid transport across the plasma membrane of many monocarboxylates. It has been reported that SLC16A7 is the primary monocarboxylate transporter in Purkinje cells and can be detected in the brain, cerebellum, liver, and kidney, but not in vascular smooth muscle cells, pericytes, endothelium, heart, lung, or stomach. There are some isoforms of SLC16A7 with bands around 52 kDa and 40-45 kDa in SDS-PAGE. The 80 kDa protein might be a dimer, similar to the papers published. (PMID: 9482213, 15749979, 11291733, 16901736)