MCT2/SLC16A7 Rekombinanter Antikörper

MCT2/SLC16A7 Rekombinant Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

242811F6

Kat-Nr. : 85145-3-RR

Synonyme

SLC16A7, MCT 2, MCT2, Monocarboxylate transporter 2, Solute carrier family 16 member 7

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  WB analysis using 85145-3-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 85145-3-RR (SLC16A7 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours.

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  Affinity and Kinetic Characterization of 85145-3-RR

  Biolayer interferometry (BLl) kinetic assays of 85145-3-RR against Human MCT2/SLC16A7 were performed. The affinity constant is 37.0 nM.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: BxPC-3-Zellen, K-562-Zellen, SH-SY5Y-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:1000-1:6000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

85145-3-RR bindet in WB, ELISA MCT2/SLC16A7 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: MCT2/SLC16A7 fusion protein Ag14201
• Vollständiger Name: solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
• Berechnetes Molekulargewicht: 478 aa, 52 kDa
• Beobachtetes Molekulargewicht: 40-52 kDa
• GenBank-Zugangsnummer: BC030693
• Gene symbol: MCT2
• Gene ID (NCBI): 9194
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SLC16A7, also named MCT2, is a proton-coupled monocarboxylate transporter catalyzing the rapid transport across the plasma membrane of many monocarboxylates. It has been reported that SLC16A7 is the primary monocarboxylate transporter in Purkinje cells and can be detected in the brain, cerebellum, liver, and kidney, but not in vascular smooth muscle cells, pericytes, endothelium, heart, lung, or stomach. There are some isoforms of SLC16A7 with bands around 52 kDa and 40-45 kDa in SDS-PAGE. The 80 kDa protein might be a dimer, similar to the papers published. (PMID: 9482213, 15749979, 11291733, 16901736)