SLC22A16 Polyklonaler Antikörper

SLC22A16 Polyklonal Antikörper für WB, IHC, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IHC, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 26833-1-PBS

Synonyme

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  WB analysis using 26833-1-AP (same clone as 26833-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 26833-1-AP (SLC22A16 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 26833-1-PBS in a different storage buffer formulation.

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  IHC staining of human breast cancer using 26833-1-AP (same clone as 26833-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 26833-1-AP (SLC22A16 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26833-1-PBS in a different storage buffer formulation.

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  IHC staining of human stomach cancer using 26833-1-AP (same clone as 26833-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue slide using 26833-1-AP (SLC22A16 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26833-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human stomach cancer using 26833-1-AP (same clone as 26833-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue slide using 26833-1-AP (SLC22A16 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26833-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 26833-1-AP (same clone as 26833-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 26833-1-AP (SLC22A16 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26833-1-PBS in a different storage buffer formulation.

• 

  IF Staining of THP-1 using 26833-1-AP (same clone as 26833-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed THP-1 cells using SLC22A16 antibody (26833-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 26833-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

26833-1-PBS bindet in WB, IHC, IF/ICC, Indirect ELISA SLC22A16 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: SLC22A16 fusion protein Ag25270
• Vollständiger Name: solute carrier family 22 (organic cation/carnitine transporter), member 16
• Berechnetes Molekulargewicht: 65 kDa
• Beobachtetes Molekulargewicht: 68 kDa
• GenBank-Zugangsnummer: BC047565
• Gene symbol: SLC22A16
• Gene ID (NCBI): 85413
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SLC22A16, also named as CT2, FLIPT2, or OCT6, belongs to the major facilitator (TC 2.A.1) superfamily and organic cation transporter (TC 2.A.1.19) family. SLC22A16 encodes an organic zwitterion transporter protein that transports carnitine and some anticancer drugs, including anthracyclines. As a carnitine transporter, SLC22A16 is involved in the regulation of fatty acid oxidation (FAO), which plays an important role also in the metabolic transformation of cancer cells. SLC22A16 expression in cancer cells is associated with increased sensitivity to the cytotoxic effects of doxorubicin. SLC22A16 has 3 isoforms with the molecular mass of 58, 61 and 65 kDa (PMID: 35761855, 35608746).