SLC22A7 Monoklonaler Antikörper

SLC22A7 Monoklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

3D3C3

Kat-Nr. : 67479-1-PBS

Synonyme

SLC22A7, 3D3C3, hOAT2, NLT, OAT2

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  WB analysis of SMMC-7721 using 67479-1-Ig (same clone as 67479-1-PBS)

  SMMC-7721 cells were subjected to SDS PAGE followed by western blot with 67479-1-Ig (SLC22A7 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67479-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver cancer using 67479-1-Ig (same clone as 67479-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 67479-1-Ig (SLC22A7 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67479-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver cancer using 67479-1-Ig (same clone as 67479-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 67479-1-Ig (SLC22A7 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67479-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver using 67479-1-Ig (same clone as 67479-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 67479-1-Ig (SLC22A7 antibody) at dilution of 1:2000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67479-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse liver using 67479-1-Ig (same clone as 67479-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 67479-1-Ig (SLC22A7 antibody) at dilution of 1:2000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67479-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

67479-1-PBS bindet in WB, IHC, Indirect ELISA SLC22A7 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Maus / IgG2a
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: SLC22A7 fusion protein Ag25234
• Vollständiger Name: solute carrier family 22 (organic anion transporter), member 7
• Berechnetes Molekulargewicht: 60 kDa
• Beobachtetes Molekulargewicht: 60 kDa
• GenBank-Zugangsnummer: BC033805
• Gene symbol: SLC22A7
• Gene ID (NCBI): 10864
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Organic anion transporter (OAT)2 (SLC22A7) belongs to the solute carrier group of membrane transport proteins that mediate cellular uptake of numerous organic ions including xenobiotics and endogenous substrates (PMID: 9529348, 20190416). SLC22A7 was originally identified as a novel liver-specific transporter because of its predominant mRNA expression in the rat liver (PMID: 15900017, 25904762). Human SLC22A7 exhibits a robust transport function for a wide array of naturally occurring nucleobases, nucleosides, and nucleotides with a particular role for cGMP (PMID: 18216183).