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SLC24A3 Polyklonaler Antikörper

SLC24A3 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 27591-1-PBS

Synonyme

NCKX3

Filter:
  • Western Blot (WB) analysis of various lysates using SLC24A3 Polyclonal antibody (27591-1-AP)

    WB analysis using 27591-1-AP (same clone as 27591-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 27591-1-AP (SLC24A3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27591-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

27591-1-PBS bindet in WB, Indirect ELISA SLC24A3 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SLC24A3 fusion protein Ag26297
Vollständiger Name solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
Berechnetes Molekulargewicht 72 kDa
Beobachtetes Molekulargewicht50-60 kDa
GenBank-ZugangsnummerNM_020689
Gene symbol SLC24A3
Gene ID (NCBI) 57419
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SLC24A3, also known as NCKX3 (Na⁺/K⁺/Ca²⁺ exchanger 3), is a member of the solute carrier family 24 (SLC24), which comprises five K⁺-dependent Na⁺/Ca²⁺ exchangers (NCKX1-5). These transporters are critical for maintaining intracellular calcium homeostasis by coupling the extrusion of one Ca²⁺ ion and one K⁺ ion to the influx of four Na⁺ ions. SLC24A3 plays a key role in calcium signaling and homeostasis, influencing processes such as neurotransmission, smooth muscle contraction, and female reproductive physiology. Relatively high levels of SLC24A3 expression can be observed in heart tissue, consistent with the expression patterns reported in the literature. The observed molecular weight of SLC24A3 is 50-60 kDa, which is consistent with the literature description. (PMID: 21573014, PMID: 28588505)