SLC24A6 Polyklonaler Antikörper

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• KD/KO Validated

SLC24A6 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 21430-1-PBS

Synonyme

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  WB analysis using 21430-1-AP (same clone as 21430-1-PBS)

  Mouse brain tissue were subjected to SDS PAGE followed by western blot with 21430-1-AP (SLC24A6 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21430-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 21430-1-AP (same clone as 21430-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 21430-1-AP (SLC24A6 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21430-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 21430-1-AP (same clone as 21430-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 21430-1-AP (SLC24A6 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21430-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 21430-1-AP (same clone as 21430-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 21430-1-AP (SLC24A6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21430-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse heart using 21430-1-AP (same clone as 21430-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 21430-1-AP (SLC24A6 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21430-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse heart using 21430-1-AP (same clone as 21430-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 21430-1-AP (SLC24A6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21430-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 21430-1-AP (same clone as 21430-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 21430-1-AP (SLC24A6 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21430-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 21430-1-AP (same clone as 21430-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 21430-1-AP (SLC24A6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21430-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

21430-1-PBS bindet in WB, IHC, Indirect ELISA SLC24A6 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: SLC24A6 fusion protein Ag16034
• Vollständiger Name: solute carrier family 24 (sodium/potassium/calcium exchanger), member 6
• Berechnetes Molekulargewicht: 584 aa, 64 kDa
• Beobachtetes Molekulargewicht: 64 kDa
• GenBank-Zugangsnummer: BC098360
• Gene symbol: SLC24A6
• Gene ID (NCBI): 80024
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SLC24A6, also named as NCLX, is a kind of mitochondrial sodium/calcium antiporter that mediates sodium-dependent calcium efflux from mitochondrion by mediating the exchange of 3 sodium ions per 1 calcium ion. It has been reported that SLC24A6 plays a key role in attenuating potential ROS production and injury upon cardiac reperfusion. SLC24A6 is associated with mitochondrial calcium homeostasis by mediating mitochondrial calcium extrusion. (PMID: 32728214, 20018762, 28219928)