SLC25A1 Rekombinanter Antikörper

• Featured Product
• KD/KO Validated

SLC25A1 Rekombinant Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

241931G11

Kat-Nr. : 84696-1-RR

Synonyme

Tricarboxylate carrier protein, SLC20A3, CTP, Citrate transport protein, CIC

---

• 

  WB analysis using 84696-1-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 84696-1-RR (SLC25A1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

• 

  WB analysis of HeLa using 84696-1-RR

  WB result of SLC25A1 antibody (84696-1-RR; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-SLC25A1 transfected HeLa cells.

---

Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: HeLa-Zellen, HEK-293-Zellen, HepG2-Zellen, NCI-H1299-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:2000-1:10000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

84696-1-RR bindet in WB, ELISA SLC25A1 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
• Berechnetes Molekulargewicht: 34 kDa
• Beobachtetes Molekulargewicht: 30 kDa
• GenBank-Zugangsnummer: BC004980
• Gene symbol: SLC25A1
• Gene ID (NCBI): 6576
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SLC25A1, also known as CIC or CTP, is a mitochondrial citrate transporter that exports citrate from the mitochondria to the cytosol. SLC25A1 is highly expressed in several tumor types. Recently it has been identified as a novel transcriptional target of mutant p53 and a negative tumor prognostic marker. In addition, defects in SLC25A1 have been found as a cause of combined D-2- and L-2-hydroxyglutaric aciduria. (PMID: 24681808, 23561848)