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SLC25A22 Rekombinanter Antikörper

SLC25A22 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250788B11

Kat-Nr. : 86163-1-PBS

Synonyme

GC 1, GC1, GC-1, Glutamate/H(+) symporter 1, NET44

Filter:
  • Western Blot (WB) analysis of various lysates using SLC25A22 Recombinant antibody (86163-1-RR)

    WB analysis using 86163-1-RR (same clone as 86163-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86163-1-RR (SLC25A22 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86163-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 86163-1-RR

    Affinity and Kinetic Characterization of 86163-1-RR

    Biolayer interferometry (BLl) kinetic assays of 86163-1-RR against Human SLC25A22 were performed. The affinity constant is 1.13 nM.

Geprüfte Anwendungen

Produktinformation

86163-1-PBS bindet in WB, Indirect ELISA SLC25A22 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen SLC25A22 fusion protein Ag19958
Vollständiger Name solute carrier family 25 (mitochondrial carrier: glutamate), member 22
Berechnetes Molekulargewicht 323 aa, 34 kDa
Beobachtetes Molekulargewicht 30-34 kDa
GenBank-ZugangsnummerBC023545
Gene symbol SLC25A22
Gene ID (NCBI) 79751
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SLC25A22 encodes a mitochondrial glutamate/H+ symporter with highly expression in brain, especially in astrocytes, where it controls glutamate uptake. The mutations of SLC25A22 are associated with the early/infantile epileptic encephalopathies. It has been shown that SLC25A22 plays a key role in promoting proliferation and migration in cancer, such as human colorectal cancer (CRC) and Gallbladder cancer (GBC). And there is a result that the expression of SLC25A22 in GBC was significantly higher than that in adjacent tissues. 25402-1-AP antibody is specific to SLC25A22.(PMID: 30814911, 25033742, 24596948)