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SLC30A1 Polyklonaler Antikörper

SLC30A1 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 22661-1-PBS

Synonyme

Zinc transporter 1, ZNT1, ZnT-1

Filter:
  • Western Blot (WB) analysis of various lysates using SLC30A1 Polyclonal antibody (22661-1-AP)

    WB analysis using 22661-1-AP (same clone as 22661-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 22661-1-AP (SLC30A1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22661-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

22661-1-PBS bindet in WB, Indirect ELISA SLC30A1 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SLC30A1 fusion protein Ag18567
Vollständiger Name solute carrier family 30 (zinc transporter), member 1
Berechnetes Molekulargewicht 507 aa, 55 kDa
Beobachtetes Molekulargewicht63~75 kDa
GenBank-ZugangsnummerBC121015
Gene symbol SLC30A1
Gene ID (NCBI) 7779
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Zinc transporter 1 (ZNT1), also known as SLC30A1, is the only zinc transporter predominantly located on the plasma membrane, where it plays a pivotal role exporting cytosolic zinc to the extracellular space. SLC30A1 expression is posttranslationally regulated by cellular zinc status and can be N-glycosylated on Asn299 in the extracellular loop between transmembrane domains (PMID: 15451416, 18936201). ZnT1 is located in the plasma membrane and is responsible for Zn export from the cytosol to the extracellular space during periods of elevated cytosolic Zn. Western analysis detected a higher band at∼63 kDa than the expected molecular mass, which could be attributed to the properties of the cytosolic histidine-rich loop (PMID: 31471319, 15753530).