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SLC31A1 Rekombinanter Antikörper

SLC31A1 Rekombinant Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

240868D10

Kat-Nr. : 83844-5-PBS

Synonyme

COPT1, 240868D10, CTR1, Truncated CTR1 form

Filter:
  • Western Blot (WB) analysis of HeLa cells using SLC31A1 Recombinant antibody (83844-5-RR)

    WB analysis of HeLa using 83844-5-RR (same clone as 83844-5-PBS)

    WB result of SLC31A1 antibody (83844-5-RR; 1:800; incubated at room temperature for 1.5 hours) with sh-Control and sh-SLC31A1 transfected HeLa cells. This data was developed using the same antibody clone with 83844-5-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using SLC31A1 Recombinant antibody (83844-5-RR)

    WB analysis using 83844-5-RR (same clone as 83844-5-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 83844-5-RR (SLC31A1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83844-5-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of SW480 cells using SLC31A1 Recombinant antibody (83844-5-RR)

    WB analysis of SW480 using 83844-5-RR (same clone as 83844-5-PBS)

    WB result of SLC31A1 antibody (83844-5-RR; 1:800; room temperature for 1.5 hours) with wild-type and SLC31A1 knockout SW480 cells. This data was developed using the same antibody clone with 83844-5-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83844-5-RR

    Affinity and Kinetic Characterization of 83844-5-RR

    Biolayer interferometry (BLl) kinetic assays of 83844-5-RR against Human SLC31A1 were performed. The affinity constant is 3.33 nM.

Geprüfte Anwendungen

Produktinformation

83844-5-PBS bindet in WB, ELISA SLC31A1 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen SLC31A1 fusion protein Ag26601
Vollständiger Name solute carrier family 31 (copper transporters), member 1
Berechnetes Molekulargewicht 21 kDa
Beobachtetes Molekulargewicht21-23 kDa
GenBank-ZugangsnummerBC013611
Gene symbol SLC31A1
Gene ID (NCBI) 1317
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SLC31A1, also known as CTR1, COPT1 and solute carrier family 31 member 1, is a high-affinity copper transporter found in the cell membrane of human cells. It plays a crucial role in maintaining copper homeostasis within the body and functions as a homotrimer to influence dietary copper absorption in the cell membrane (PMID: 37853210; 28507097). SLC31A1 has three putative transmembrane domains, with an N-terminus located extracellularly and a C-terminus located intracellularly (PMID: 12827356). SLC31A1 can be detected a a 28 kDa band corresponding to glycosylated hCTR1 monomer, and a 24 kDa band that is unglycosylated hCTR1. In some membrane preparations a C-terminal degradation product of 17 kDa is also seen (PMID: 16135512). Additionally, SLC31A1 may also resolve as a 30 to 35 kDa and a 60 to 70 kDa protein on immunoblots, forming oligomers corresponding to the expected size of a homotrimeric complex (PMID: 12827356).