SLC6A7 Rekombinanter Antikörper

SLC6A7 Rekombinant Antikörper für IHC, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

IHC, ELISA

Konjugation

Unkonjugiert

CloneNo.

240395H5

Kat-Nr. : 83412-4-PBS

Synonyme

Sodium-dependent proline transporter, PROT, 240395H5

---

• 

  IHC staining of mouse brain using 83412-4-RR (same clone as 83412-4-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 83412-4-RR (SLC6A7 antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83412-4-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 83412-4-RR (same clone as 83412-4-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 83412-4-RR (SLC6A7 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83412-4-PBS in a different storage buffer formulation.

• 

  IHC staining of rat brain using 83412-4-RR (same clone as 83412-4-PBS)

  Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 83412-4-RR (SLC6A7 antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83412-4-PBS in a different storage buffer formulation.

• 

  IHC staining of rat brain using 83412-4-RR (same clone as 83412-4-PBS)

  Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 83412-4-RR (SLC6A7 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83412-4-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 83412-4-RR

  Biolayer interferometry (BLl) kinetic assays of 83412-4-RR against Human SLC6A7 were performed. The affinity constant is below 1 pM.

---

Geprüfte Anwendungen

Produktinformation

83412-4-PBS bindet in IHC, ELISA SLC6A7 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: SLC6A7 fusion protein Ag34413
• Vollständiger Name: solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
• Berechnetes Molekulargewicht: 636 aa, 71 kDa
• GenBank-Zugangsnummer: BC093785
• Gene symbol: SLC6A7
• Gene ID (NCBI): 6534
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SLC6A7 also known as PROT, belongs to the solute Carrier 6 gene family. SLC6A7 is a high-affinity mammalian brain L-proline transporter, which is different from other sodium-dependent plasma membrane carriers, and has unique pharmacological specificity, kinetic properties, and ionic requirements. SLC6A7 is a brain specific sodium (and chloride)-dependent proline transporter, that terminates the action of proline by its high affinity sodium-dependent reuptake into presynaptic terminals(PMID: 7651355).