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SLC7A2 Polyklonaler Antikörper

SLC7A2 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 30232-1-PBS

Synonyme

HCAT2, Cationic amino acid transporter 2, CAT-2

Filter:
  • Western Blot (WB) analysis of various lysates using SLC7A2 Polyclonal antibody (30232-1-AP)

    WB analysis using 30232-1-AP (same clone as 30232-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30232-1-AP (SLC7A2 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30232-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human stomach cancer tissue using SLC7A2 Polyclonal antibody (30232-1-AP)

    IHC staining of human stomach cancer using 30232-1-AP (same clone as 30232-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue slide using 30232-1-AP (SLC7A2 antibody) at dilution of 1:160 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30232-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

30232-1-PBS bindet in WB, IHC, Indirect ELISA SLC7A2 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SLC7A2 fusion protein Ag31207
Vollständiger Name solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
Berechnetes Molekulargewicht 698 aa, 76 kDa
Beobachtetes Molekulargewicht 76 kDa
GenBank-ZugangsnummerBC104905
Gene symbol SLC7A2
Gene ID (NCBI) 6542
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Solute carrier family 7 member 2 (SLC7A2), also known as CAT2, is a member of the solute carrier superfamily. It functions as a cationic amino acid transporter, which can transport cationic amino acids (arginine, lysine and ornithine) into the cytosol and regulate inflammation (PMID: 35152203). It has been shown that lower SLC7A2 expression is associated with worse prognosis of ovarian cancer and hepatocellular carcinoma (PMID: 34108444; 32647070), and SLC7A2 deficiency in inflammatory bowel tissues increases the risk of inflammation-associated colon tumorigenesis (PMID: 30202097)