SLCO1B3/OATP1B3 Polyklonaler Antikörper

SLCO1B3/OATP1B3 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 22815-1-PBS

Synonyme



Geprüfte Anwendungen

Produktinformation

22815-1-PBS bindet in WB, Indirect ELISA SLCO1B3/OATP1B3 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SLCO1B3/OATP1B3 fusion protein Ag18940
Vollständiger Name solute carrier organic anion transporter family, member 1B3
Berechnetes Molekulargewicht 702 aa, 77 kDa
Beobachtetes Molekulargewicht 70-75 kDa
GenBank-ZugangsnummerBC105597
Gene symbol SLCO1B3
Gene ID (NCBI) 28234
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SLCO1B3, also known as OATP8 or OATP1B3, is a member of Organic Anion Transporting Polypeptides (OATPs) which are sodium-independent organic anion transporters mediating the uptake of a wide range of structurally diverse endogenous and exogenous compounds including bile acids, hormone conjugates, peptides, toxins, as well as a multitude of therapeutic drugs. SLCO1B3 is specifically expressed in liver under normal condition, while its expression has also been observed in cancer tissues like colon, prostate and pancreas. SLCO1B3 is a glycosylated protein and can be detected in the non-glycosylated form at 70-75 kDa(PMID: 21278621).