SLCO1B3/OATP1B3 Polyklonaler Antikörper
SLCO1B3/OATP1B3 Polyklonal Antikörper für WB, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human
Anwendung
WB, Indirect ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 22815-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
22815-1-PBS bindet in WB, Indirect ELISA SLCO1B3/OATP1B3 und zeigt Reaktivität mit human
| Getestete Reaktivität | human |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Polyklonal |
| Typ | Antikörper |
| Immunogen | SLCO1B3/OATP1B3 fusion protein Ag18940 |
| Vollständiger Name | solute carrier organic anion transporter family, member 1B3 |
| Berechnetes Molekulargewicht | 702 aa, 77 kDa |
| Beobachtetes Molekulargewicht | 70-75 kDa |
| GenBank-Zugangsnummer | BC105597 |
| Gene symbol | SLCO1B3 |
| Gene ID (NCBI) | 28234 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Antigen-Affinitätsreinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
SLCO1B3, also known as OATP8 or OATP1B3, is a member of Organic Anion Transporting Polypeptides (OATPs) which are sodium-independent organic anion transporters mediating the uptake of a wide range of structurally diverse endogenous and exogenous compounds including bile acids, hormone conjugates, peptides, toxins, as well as a multitude of therapeutic drugs. SLCO1B3 is specifically expressed in liver under normal condition, while its expression has also been observed in cancer tissues like colon, prostate and pancreas. SLCO1B3 is a glycosylated protein and can be detected in the non-glycosylated form at 70-75 kDa(PMID: 21278621).

