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SLCO2B1 Polyklonaler Antikörper

SLCO2B1 Polyklonal Antikörper für WB, IHC, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 55180-1-PBS

Synonyme

SLC21A9, OATPRP2, OATPB, OATP2B1, OATP B

Filter:
  • Western Blot (WB) analysis of various lysates using SLCO2B1 Polyclonal antibody (55180-1-AP)

    WB analysis using 55180-1-AP (same clone as 55180-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 55180-1-AP (SLCO2B1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55180-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using SLCO2B1 Polyclonal antibody (55180-1-AP)

    WB analysis using 55180-1-AP (same clone as 55180-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 55180-1-AP (SLCO2B1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55180-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human liver tissue using SLCO2B1 Polyclonal antibody (55180-1-AP)

    IHC staining of human liver using 55180-1-AP (same clone as 55180-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 55180-1-AP (SLCO2B1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 55180-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of HepG2 cells using SLCO2B1 Polyclonal antibody (55180-1-AP)

    IF Staining of HepG2 using 55180-1-AP (same clone as 55180-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using SLCO2B1 antibody (55180-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), CL594-phalloidin (red). This data was developed using the same antibody clone with 55180-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

55180-1-PBS bindet in WB, IHC, IF/ICC, Indirect ELISA SLCO2B1 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Peptid
Vollständiger Name solute carrier organic anion transporter family, member 2B1
Berechnetes Molekulargewicht 77 kDa
Beobachtetes Molekulargewicht61~74 kDa
GenBank-ZugangsnummerNM_007256
Gene symbol SLCO2B1
Gene ID (NCBI) 11309
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Solute carrier organic anion (SLCO) gene families encode organic anion transport proteins (OATP), which are membrane transporters widely expressed in the human body that influx numerous compounds and drugs including androgens. SLCO2B1 is a member of an organic anion transporter family and has previously been shown to transport a multitude of drugs and steroid hormone conjugates (PMID: 35714613). High expression of SLCO2B1 is known to associate with the resistance to androgen deprivation therapy in prostate cancer (PMID: 29581838).