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SLCO2B1 Rekombinanter Antikörper

SLCO2B1 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241199F9

Kat-Nr. : 84353-1-PBS

Synonyme

OATPRP2, OATPB, OATP2B1, OATP B, KIAA0880

Filter:
  • Western Blot (WB) analysis of various lysates using SLCO2B1 Recombinant antibody (84353-1-RR)

    WB analysis using 84353-1-RR (same clone as 84353-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84353-1-RR (SLCO2B1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84353-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

84353-1-PBS bindet in WB, Indirect ELISA SLCO2B1 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Peptid
Vollständiger Name solute carrier organic anion transporter family, member 2B1
Berechnetes Molekulargewicht 77 kDa
Beobachtetes Molekulargewicht61~74 kDa
GenBank-ZugangsnummerNM_007256
Gene symbol SLCO2B1
Gene ID (NCBI) 11309
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Solute carrier organic anion (SLCO) gene families encode organic anion transport proteins (OATP), which are membrane transporters widely expressed in the human body that influx numerous compounds and drugs including androgens. SLCO2B1 is a member of an organic anion transporter family and has previously been shown to transport a multitude of drugs and steroid hormone conjugates (PMID: 35714613). High expression of SLCO2B1 is known to associate with the resistance to androgen deprivation therapy in prostate cancer (PMID: 29581838). OATP2B1 was insensitive to endoglycosidase H, an enzyme that cleaves only high mannose glycans, as expected for a mature protein undergoing complex glycosylation.