SMC2 Rekombinanter Antikörper

SMC2 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241536E1

Kat-Nr. : 84835-2-PBS

Synonyme

SMC protein 2, SMC 2, hCAP E, CAPE, CAP E

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  WB analysis using 84835-2-RR (same clone as 84835-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84835-2-RR (SMC2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84835-2-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84835-2-RR

  Biolayer interferometry (BLl) kinetic assays of 84835-2-RR against Human SMC2 were performed. The affinity constant is below 1 pM.

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Geprüfte Anwendungen

Produktinformation

84835-2-PBS bindet in WB, Indirect ELISA SMC2 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: SMC2 fusion protein Ag33471
• Vollständiger Name: structural maintenance of chromosomes 2
• Berechnetes Molekulargewicht: 136 kDa
• Beobachtetes Molekulargewicht: 135-140 kDa
• GenBank-Zugangsnummer: NM_001042550.1
• Gene symbol: SMC2
• Gene ID (NCBI): 10592
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SMC2 is a central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (PMID: 11136719).