SMPD1,ASM Polyklonaler Antikörper

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SMPD1,ASM Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 14609-1-PBS

Synonyme

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  WB analysis using 14609-1-AP (same clone as 14609-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 14609-1-AP (SMPD1,ASM antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14609-1-PBS in a different storage buffer formulation.

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  IHC staining of human brain using 14609-1-AP (same clone as 14609-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 14609-1-AP (SMPD1,ASM Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14609-1-PBS in a different storage buffer formulation.

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  IHC staining of human brain using 14609-1-AP (same clone as 14609-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 14609-1-AP (SMPD1,ASM Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14609-1-PBS in a different storage buffer formulation.

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  IHC staining of human tonsillitis using 14609-1-AP (same clone as 14609-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 14609-1-AP (SMPD1,ASM Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14609-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human tonsillitis using 14609-1-AP (same clone as 14609-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 14609-1-AP (SMPD1,ASM Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14609-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

14609-1-PBS bindet in WB, IHC, Indirect ELISA SMPD1,ASM und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: SMPD1,ASM fusion protein Ag6180
• Vollständiger Name: sphingomyelin phosphodiesterase 1, acid lysosomal
• Berechnetes Molekulargewicht: 70 kDa
• Beobachtetes Molekulargewicht: 60 kDa, 70-75 kDa
• GenBank-Zugangsnummer: BC041164
• Gene symbol: SMPD1
• Gene ID (NCBI): 6609
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SMPD1(Sphingomyelin phosphodiesterase) is also named as ASM and belongs to the acid sphingomyelinase family. It is an important enzyme in sphingolipid metabolism and plays key roles in apoptosis, immunity, development, and cancer. The deficient activity of this enzyme results in Types A and B Niemann-Pick disease (NPD). This protein has 4 isoforms produced by alternative splicing. SMPD1 can produce a 60 kDa peptide with its signal peptide missing.