SMYD4 Polyklonaler Antikörper

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• KD/KO Validated

SMYD4 Polyklonal Antikörper für WB, IHC, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Ratte

Anwendung

WB, IHC, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 17594-1-PBS

Synonyme

ZMYND21, SMYD 4, SET and MYND domain-containing protein 4, EC:2.1.1.-

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  WB analysis of HepG2 using 17594-1-AP (same clone as 17594-1-PBS)

  HepG2 cells were subjected to SDS PAGE followed by western blot with 17594-1-AP (SMYD4 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17594-1-PBS in a different storage buffer formulation.

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  IHC staining of human pancreas using 17594-1-AP (same clone as 17594-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas using 17594-1-AP (SMYD4 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 17594-1-PBS in a different storage buffer formulation.

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  IHC staining of human pancreas using 17594-1-AP (same clone as 17594-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas using 17594-1-AP (SMYD4 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 17594-1-PBS in a different storage buffer formulation.

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  IHC staining of human hepatocirrhosis using 17594-1-AP (same clone as 17594-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human hepatocirrhosis using 17594-1-AP (SMYD4 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 17594-1-PBS in a different storage buffer formulation.

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  IHC staining of human hepatocirrhosis using 17594-1-AP (same clone as 17594-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human hepatocirrhosis using 17594-1-AP (SMYD4 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 17594-1-PBS in a different storage buffer formulation.

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  IF Staining of HepG2 using 17594-1-AP (same clone as 17594-1-PBS)

  Immunofluorescent analysis of (-20℃ Ethanol) fixed HepG2 cells using 17594-1-AP (SMYD4 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 17594-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

17594-1-PBS bindet in WB, IHC, IF/ICC, Indirect ELISA SMYD4 und zeigt Reaktivität mit human, Ratten

• Getestete Reaktivität: human, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: SMYD4 fusion protein Ag11552
• Vollständiger Name: SET and MYND domain containing 4
• Berechnetes Molekulargewicht: 804 aa, 89 kDa
• Beobachtetes Molekulargewicht: 89 kDa
• GenBank-Zugangsnummer: BC035077
• Gene symbol: SMYD4
• Gene ID (NCBI): 114826
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SMYD4, also named as SET and MYND domain-containing protein 4, is a 804 amino acid protein, which contains 1 MYND-type zinc finger and 1 SET domain. SMYD4 belongs to the class V-like SAM-binding methyltransferase superfamily. SMYD4, as a potential tumor suppressor, plays a critical role in breast carcinogenesis at least partly through inhibiting the expression of Pdgfr-alpha, and could be a novel target for improving treatment of breast cancer. SMYD4 is a muscle-specific transcriptional modulator involved in development.