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SNAI1 Rekombinanter Antikörper

SNAI1 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

230035C9

Kat-Nr. : 82214-2-PBS

Synonyme

dJ710H13.1, Protein sna, Protein snail homolog 1, SLUGH2, SNA, SNAH, SNAI1, snail homolog 1 (Drosophila), SNAIL1, Zinc finger protein SNAI1

Filter:
  • Western Blot (WB) analysis of HeLa cells using SNAI1 Recombinant antibody (82214-2-RR)

    WB analysis of HeLa using 82214-2-RR (same clone as 82214-2-PBS)

    HeLa cells were subjected to SDS PAGE followed by western blot with 82214-2-RR (SNAI1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82214-2-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 82214-2-PBS

    Affinity and Kinetic Characterization of 82214-2-PBS

    Biolayer interferometry (BLl) kinetic assays of 82214-2-RR against Human SNAI1 were performed. The affinity constant is below 1 pM.

Geprüfte Anwendungen

Produktinformation

82214-2-PBS bindet in WB, Indirect ELISA SNAI1 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen SNAI1 fusion protein Ag3723
Vollständiger Name snail homolog 1 (Drosophila)
Berechnetes Molekulargewicht 264 aa, 29 kDa
Beobachtetes Molekulargewicht35 kDa
GenBank-ZugangsnummerBC012910
Gene symbol SNAI1
Gene ID (NCBI) 6615
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SNAI1, a member of SNAI1 family of protein, participates in the epithelial to mesenchymal transition(EMT) and formation and maintenance of embryonic mesoderm. The snail family share a common structural, that a highly conserved C-terminal region containing a zinc finger transcription factor. SNAI1 interacts with other corepressor, such as Ajuba, PRMT5 and SIN3a or HDAC1 and 2, to repress the target gene. As the phosphorylation modification of SNAI1 protein, the range of molecular weight of SNAI1 is about 25-30 kDa (PMID: 22276203 ). Once phosphorylated (probably on Ser-107, Ser-111, Ser-115 and Ser-119) it is exported from the nucleus to the cytoplasm where subsequent phosphorylation of the destruction motif and ubiquitination involving BTRC occurs.