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SNIP/p140Cap Polyklonaler Antikörper

SNIP/p140Cap Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 29890-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using SNIP/p140Cap Polyclonal antibody (29890-1-AP)

    WB analysis using 29890-1-AP (same clone as 29890-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 29890-1-AP (SNIP antibody) at dilution of 1:30000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29890-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

29890-1-PBS bindet in WB, Indirect ELISA SNIP/p140Cap und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SNIP/p140Cap fusion protein Ag31857
Vollständiger Name SNAP25-interacting protein
Berechnetes Molekulargewicht127 kDa
Beobachtetes Molekulargewicht145 kDa
Gene symbol SNIP
Gene ID (NCBI) 80725
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SNIP, also named SRC kinase signaling inhibitor 1 (SRCIN1) and p140 Cas-associated protein (p140CAP), contains two regions of highly charged amino acids, two proline-rich regions, and two coiled-coil domains. SNIP plays a role in SRC inactivation and acts as a tumor suppressor gene in cancers. MiR-32 suppresses the expression of SNIP, thereby suppressing proliferation and epithelial-mesenchymal transition (EMT) of human liver cancer cells (PMID: 28550679).