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SNRNP200 Rekombinanter Antikörper

SNRNP200 Rekombinant Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242550D10

Kat-Nr. : 84992-5-PBS

Synonyme

242550D10, Activating signal cointegrator 1 complex subunit 3-like 1, ASCC3L1, BRR2, EC:3.6.4.13

Filter:
  • Western Blot (WB) analysis of various lysates using SNRNP200 Recombinant antibody (84992-5-RR)

    WB analysis using 84992-5-RR (same clone as 84992-5-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84992-5-RR (SNRNP200 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84992-5-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human placenta tissue using SNRNP200 Recombinant antibody (84992-5-RR)

    IHC staining of human placenta using 84992-5-RR (same clone as 84992-5-PBS)

    Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 84992-5-RR (SNRNP200 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84992-5-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human placenta tissue using SNRNP200 Recombinant antibody (84992-5-RR)

    IHC staining of human placenta using 84992-5-RR (same clone as 84992-5-PBS)

    Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 84992-5-RR (SNRNP200 antibody) at dilution of 1:1000 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84992-5-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

84992-5-PBS bindet in WB, IHC, Indirect ELISA SNRNP200 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen SNRNP200 fusion protein Ag20748
Vollständiger Name small nuclear ribonucleoprotein 200kDa (U5)
Berechnetes Molekulargewicht 494 aa, 57 kDa
Beobachtetes Molekulargewicht200-245 kDa
GenBank-ZugangsnummerBC001417
Gene symbol SNRNP200
Gene ID (NCBI) 23020
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SNRNP200 (small nuclear ribonucleoprotein 200kDa (U5)), also known as HELIC2, ASCC3L1 or BRR2, is a 2,136 amino acid protein that localizes to the nucleus and contains two SEC63 domains, two helicase C-terminal domains and two helicase ATP-binding domains. Existing as multiple alternatively spliced isoforms, HELIC2 functions as an RNA helicase that is thought to promote specific RNA-RNA conformational changes which are important in the second step of RNA splicing. The gene encoding HELIC2 maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the chromosome 2-localized ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes, hich also map to chromosome 2. The observed molecular weight of SNRNP200 is 200-245kd.