SNRPD1 Polyklonaler Antikörper

SNRPD1 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 10352-1-PBS

Synonyme

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  WB analysis of HEK-293 using 10352-1-AP (same clone as 10352-1-PBS)

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 10352-1-AP (SNRPD1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10352-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HEK-293 using 10352-1-AP (same clone as 10352-1-PBS)

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 10352-1-AP (SNRPD1 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10352-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HL-60 using 10352-1-AP (same clone as 10352-1-PBS)

  HL-60 cells were subjected to SDS PAGE followed by western blot with 10352-1-AP (SNRPD1 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10352-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

10352-1-PBS bindet in WB, Indirect ELISA SNRPD1 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: SNRPD1 fusion protein Ag0364
• Vollständiger Name: small nuclear ribonucleoprotein D1 polypeptide 16kDa
• Berechnetes Molekulargewicht: 16 kDa
• Beobachtetes Molekulargewicht: 13 kDa
• GenBank-Zugangsnummer: BC001721
• Gene symbol: SNRPD1
• Gene ID (NCBI): 6632
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Systemic lupus erythematosus is characterized by antibodies to a variety of intracellular self-antigens, such as dsDNA and Sm, and these serve as hallmarks in the diagnosis of systemic autoimmune diseases. SNRPD1 is one Sm components of the small nuclear ribonucleoprotein complexes(snRNPs). It's a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through nonspecific electrostatic contacts with RNA. This antibody detectes 13-16 kDa (SMD1) and 30 kDa (SMD1/SMD2 dimer form; PMID:15525645).

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