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SNTA1 Polyklonaler Antikörper

SNTA1 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 13131-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using SNTA1 Polyclonal antibody (13131-1-AP)

    WB analysis using 13131-1-AP (same clone as 13131-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 13131-1-AP (SNTA1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13131-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse heart tissue using SNTA1 Polyclonal antibody (13131-1-AP)

    IHC staining of mouse heart using 13131-1-AP (same clone as 13131-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 13131-1-AP (SNTA1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13131-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse heart tissue using SNTA1 Polyclonal antibody (13131-1-AP)

    IHC staining of mouse heart using 13131-1-AP (same clone as 13131-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 13131-1-AP (SNTA1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13131-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

13131-1-PBS bindet in WB, IHC, Indirect ELISA SNTA1 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SNTA1 fusion protein Ag3820
Vollständiger Name syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)
Berechnetes Molekulargewicht 505 aa, 54 kDa
Beobachtetes Molekulargewicht 54 kDa
GenBank-ZugangsnummerBC026215
Gene symbol SNTA1
Gene ID (NCBI) 6640
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SNTA1, also known as Syntrophin 1, SNT1, is cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex. SNTA1 is a signal-transducing adaptor protein and serves as a scaffold for various signaling molecules. Alpha-1 syntrophin contains a PDZ domain, two Pleckstrin homology domains, and a 'syntrophin unique' domain. SNTA1 is the high expression in skeletal muscle and heart (PMID: 8576247, 8612778,). The PDZ domain of SNTA1 has been reported to bind to the C-terminal domain of murine cardiac voltage-gated sodium channels (SkM2) causing altering ion channel activity leading to Long QT syndrome(PMID 19684871, 19862833).