• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

SOCS3 Rekombinanter Antikörper

SOCS3 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242809D7

Kat-Nr. : 85155-4-PBS

Synonyme

242809D7, ATOD4, CIS3, CIS-3, Cytokine-inducible SH2 protein 3

Filter:
  • Western Blot (WB) analysis of various lysates using SOCS3 Recombinant antibody (85155-4-RR)

    WB analysis using 85155-4-RR (same clone as 85155-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85155-4-RR (SOCS3 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85155-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 85155-4-RR

    Affinity and Kinetic Characterization of 85155-4-RR

    Biolayer interferometry (BLl) kinetic assays of 85155-4-RR against Human SOCS3 were performed. The affinity constant is below 1 pM.

Geprüfte Anwendungen

Produktinformation

85155-4-PBS bindet in WB, Indirect ELISA SOCS3 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen SOCS3 fusion protein Ag5170
Vollständiger Name suppressor of cytokine signaling 3
Berechnetes Molekulargewicht 25 kDa
Beobachtetes Molekulargewicht 25-30 kDa
GenBank-ZugangsnummerBC060858
Gene symbol SOCS3
Gene ID (NCBI) 9021
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The suppressor of cytokine signaling (SOCS) family proteins are negative feedback system that inhibits cytokine signal transduction. One of the SOCS family, SOCS3, also named CIS3 and SSI3, is involved in inhibition of JAK/STAT pathway which regulates IL-6 signaling in vivo. SOCS3 can be rapidly trigger by a number of factors including interleukins, IFN-gamma and TNF-alpha. Pathology such as inflammatory response, wound repair and obesity and so on have been linked to SOCS3. Observed MW of SOCS3 is from 22-30 kDa(PMID: 24827536,PMID: 26260587, PMID: 26797799).