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SOD1 Rekombinanter Antikörper

SOD1 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

240888B9

Kat-Nr. : 83857-6-PBS

Synonyme

IPOA, hSod1, homodimer, EC:1.15.1.1, ALS1

Filter:
  • Western Blot (WB) analysis of various lysates using SOD1 Recombinant antibody (83857-6-RR)

    WB analysis using 83857-6-RR (same clone as 83857-6-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 83857-6-RR (SOD1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83857-6-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83857-6-RR

    Affinity and Kinetic Characterization of 83857-6-RR

    Biolayer interferometry (BLl) kinetic assays of 83857-6-RR against Human SOD1 were performed. The affinity constant is 13.0 nM.

Geprüfte Anwendungen

Produktinformation

83857-6-PBS bindet in WB, Indirect ELISA SOD1 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Rekombinantes Protein
Vollständiger Name superoxide dismutase 1, soluble
Berechnetes Molekulargewicht16kDa
Beobachtetes Molekulargewicht16-20 kDa
GenBank-ZugangsnummerNM_000454.5
Gene symbol SOD1
Gene ID (NCBI) 6647
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) (SOD1, synonyms: ALS, SOD, ALS1, IPOA) binds copper and zinc ions and is one of two isozymes responsible for destroying free uperoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis.